A general method for the preparation of 1,1-bis(trifluoromethyl)substituted olefins

Autor:	Hengyao Lu, Donald J. Burton
Rok vydání:	1995
Předmět:	Diethylaminosulfur trifluoride chemistry.chemical_compound General method Trifluoromethyl chemistry Organic Chemistry Drug Discovery Organic chemistry Regioselectivity Biochemistry
Zdroj:	Tetrahedron Letters. 36:3973-3976
ISSN:	0040-4039
DOI:	10.1016/0040-4039(95)00691-5
Popis:	The title compounds are prepared by treatment of 1,1-difluoro-2-trifluoromethyl-1-alken-3-ols ( 1 ) with diethylaminosulfur trifluoride (DAST) with high regioselectivity. The alcohols ( 1 ) are obtained by the reaction of 2-pentafluoropropenyllithium with aldehydes and ketones.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2234a584f692259bac9e1ae2be1c2b73 https://doi.org/10.1016/0040-4039(95)00691-5 Zobrazit plný text záznamu Full Text from ScienceDirect