Mussel-inspired synthesis of magnetic N-Halamine nanoparticles for antibacterial recycling
| Autor: | Lifang Wang, Yue Gao, Heyuan Wang, Danxia Chai, Xiufeng Hao, Ge Gao, Wenxin Liu, Huihui Qu, Alideertu Dong, Yujiao Hao, Haixiao Wang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
biology
Chemistry Biofilm Nanoparticle 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology biology.organism_classification medicine.disease_cause 01 natural sciences Combinatorial chemistry 0104 chemical sciences Surfaces Coatings and Films Colloid and Surface Chemistry Materials Chemistry Copolymer medicine Surface modification Adhesive Physical and Theoretical Chemistry 0210 nano-technology Antibacterial activity Escherichia coli Bacteria Biotechnology |
| Zdroj: | Colloid and Interface Science Communications. 39:100320 |
| ISSN: | 2215-0382 |
| DOI: | 10.1016/j.colcom.2020.100320 |
| Popis: | Antibacterial N-halamine coatings are successful in avoiding and eliminating bacterial infections caused by bacterial contamination and biofilms on the surfaces. However, the N-halamine coatings remain a long-standing challenge faced by our healthcare system. Herein we reported a new mussel-inspired surface modification strategy to achieve N-halamine copolymer coatings with adhesive effects. The phenolic hydroxyl groups from N-halamine copolymers are used for ligand exchange with oleic acid on the magnetic Fe3O4 nanoparticles for binding the N-halamine copolymer onto the surface of the nanoparticles. The as-synthesized N-halamine coatings endow the magnetic Fe3O4 nanoparticles antibacterial activity toward both Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). Since the super-paramagnetism of Fe3O4 in core, the N-halamine coatings are separable magnetically and remain high inactivating efficiency toward bacteria even after five cycles. We believe that, with the advantage of mussel-inspired strategy, the N-halamine coatings should have great potential for use in antibacterial and biomedical fields. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect