Receptor-Free Signaling at Curved Cellular Membranes

Autor: Ebrahimkutty, Mirsana P., Galic, Milos
Jazyk: angličtina
Rok vydání: 2019
DOI: 10.23689/fidgeo-4512
Popis: Plasma membranes are subject to continuous deformations. Strikingly, some of these transient membrane undulations yield membrane-associated signaling hubs that differ in composition and function, depending on membrane geometry and the availability of co-factors. Here, recent advancements on this ubiquitous type of receptor-independent signaling are reviewed, with a special focus on emerging concepts and technical challenges associated with studying these elusive signaling sites.
Databáze: OpenAIRE