Extensive peritoneal implant metastases of malignant struma ovarii treated by thyroidectomy and 131I therapy
| Autor: | dong Duan, Mengxue Wu, Xing Huang, Chengming Lei, Fengqiong Hu, Zuwen Tan |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Thyroid Thyroidectomy Sigmoid colon 030209 endocrinology & metabolism General Medicine Malignant Struma Ovarii Pelvic cavity medicine.disease Metastasis Thyroid carcinoma 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Medicine Radiology business Thyroid cancer |
| Zdroj: | Medicine. 97:e13867 |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | Rationale Malignant struma ovarii is extremely rare in the clinic. The diagnosis and modalities of treatment are still controversial. Here we describe a case of extensive peritoneal implant metastasis originating from malignant struma ovarii discovered 14 years after ovariectomy and chemotherapy. Patient concerns A 48-year-old female was admitted to our clinic due to hematochezia with a past history of left malignant struma ovarii. Enhanced computed tomography (CT) examination suggested multiple metastasis nodules in the abdomen and pelvic cavity. Diagnoses Laparoscopy biopsy results of intraperitoneal nodules showed a metastasis of papillary thyroid carcinoma. While pathological examination after total thyroidectomy showed no definite malignant tumor component in the thyroid tissue. Finally, combined with the patient's past history of malignant struma ovarii, peritoneal implantation metastasis derived from the malignant struma ovarii was diagnosed. Interventions The patient was treated by total thyroidectomy and iodine 131 (I) therapy. Post-therapy iodine scan and the single-photon emission computed tomography/computed tomography (SPECT/CT) fusion image showed iodine uptake in the distal descending colon, sigmoid colon, rectal lesions, and a larger lesion in the liver. Outcome After treatment, although the thyroid globulin remained at a high level 3 months after treatment, the patient's hematochezia was relieved. Lessons Therefore, thyroidectomy followed by adjuvant I treatment should be recommended in patients with malignant struma ovarii as metastatic risk is difficult to predict based on histopathologic examination. |
| Databáze: | OpenAIRE |
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