Survey of peridomestic mammal susceptibility to SARS-CoV-2 infection

Autor: Audrey E Walker, Rachel M. Maison, Pepper A, Angela M. Bosco-Lauth, Helle Bielefeldt-Ohmann, Stephanie M. Porter, J. Jeffrey Root, Richard A. Bowen, Airn-Elizabeth Hartwig, Paul Gordy, Lauren Guilbert, Hawvermale D
Rok vydání: 2021
Předmět:
Popis: Wild animals have been implicated as the origin of SARS-CoV-2, but it is largely unknown how the virus affects most wildlife species and if wildlife could ultimately serve as a reservoir for maintaining the virus outside the human population. Here we show that several common peridomestic species, including deer mice, bushy-tailed woodrats, and striped skunks, are susceptible to infection and can shed the virus in respiratory secretions. In contrast, we demonstrate that cottontail rabbits, fox squirrels, Wyoming ground squirrels, black-tailed prairie dogs, house mice, and racoons are not susceptible to SARS-CoV-2 infection. Our work expands upon the existing knowledge base of susceptible species and provides evidence that human-wildlife interactions could result in continued transmission of SARS-CoV-2.
Databáze: OpenAIRE