Comparison of treatment modalities regarding the entity of the trapped fourth ventricle: A 20-year retrospective analysis of our clinical experience
| Autor: | Dimitrios Panagopoulos, Georgios Stranjalis, Maro Gavra, Efstathios Boviatsis, Stefanos Korfias, Ploutarchos Karydakis, Marios Tmemistocleous |
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| Rok vydání: | 2022 |
| Zdroj: | Medical Research Archives. 10 |
| ISSN: | 2375-1924 2375-1916 |
| Popis: | Introduction: The entity of the trapped fourth ventricle represents a clinical challenge, as it is a rare entity associated with a wide spectrum of underlying pathologic conditions and the proposed treatment options are restricted and frequently associated with complications and unfavorable long-term outcome. The majority of the affected individuals report a medical history of previous ventriculo-peritoneal shunt infection, as well as a precipitating factor for the entrapment (central nervous system infection, intraventricular hemorrhage, trauma). They come to clinical attention due to symptomatology attributed to mass effect that is exerted by the ballooned fourth ventricle on the brainstem and cerebellum. Materials and Methods: We present our results, extracted from data derived from our medical center 20 years surgical experience and relevant outcomes in 120 pediatric patients diagnosed and managed with entrapped fourth ventricle. They were treated either with fourth ventricle-peritoneal shunt insertion or with an endoscopic approach. The relative efficacy of both techniques was recorded one year and five years after the initial operation and the data underwent statistical analysis. All patients who failed the initial therapeutic option were managed again with the aforementioned techniques, and their long-term results were recorded. Conclusions: We recorded that after one year of follow-up, there were no significant differences in outcome when these two techniques were compared. However, when the results of five-year follow-up were compared between two groups, there was superiority, regarding the functional outcome, of the procedure involving the insertion of a fourth ventricular-peritoneal shunt. The outcome of patients that underwent a salvage procedure of any type did not seem to be different after a one-year follow-up period, being unable to verify the superiority of one technique over the other. However, there seems to be a superiority of the shunt procedure over the endoscopic technique regarding the functional outcome of these patients, five years after their second operation. Nevertheless, these results are only indicative and our data are insufficient to establish a statistical level of significance, probably due to the restricted number of patients that were incorporated in our survey. |
| Databáze: | OpenAIRE |
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