Arylation of pyridine N-oxides via a ligand-free Suzuki reaction in water

Autor:	Yixia Zhang, Shao-Ke Zhang, Chun Liu, Zilin Jin
Rok vydání:	2015
Předmět:	chemistry.chemical_compound chemistry Suzuki reaction Ligand Pyridine Polymer chemistry Oxide chemistry.chemical_element Organic chemistry Diisopropylamine General Chemistry Palladium
Zdroj:	Chinese Chemical Letters. 26:55-57
ISSN:	1001-8417
Popis:	We report a practical and highly efficient protocol for the arylation of pyridine N -oxides with arylboronic acid through palladium-catalyzed Suzuki reaction in water. This ligand-free Suzuki reaction is performed in the presence of diisopropylamine and gives 2- or 3-arylated pyridyl N -oxide derivatives in good to excellent yields within 1 h.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2206d5a29690150492a76683969f5431 https://doi.org/10.1016/j.cclet.2014.09.019 Zobrazit plný text záznamu Full Text from ScienceDirect