ARE TUMORAL MARKERS PREDICTIVE FACTORS FOR MOLECULAR SUBTYPES IN BREAST CANCER?

Autor: V. Munteanu, Monica Cirstoiu, Georgiana Radu
Rok vydání: 2019
Předmět:
Zdroj: Journal of Surgical Sciences. 5:189-194
ISSN: 2457-5364
2360-3038
Popis: Breast cancer kills more women annually than any other type of neoplasm. Even though he has shown a particular interest in the medical body since ancient times, the very heterogeneous nature of the tumors and their versatility have made it difficult to find a diagnostic and therapeutic consensus that fully characterizes this pathology and describes its evolution. Immunohistochemical methods manage to outline a gene-molecular profile depending on the biomarkers expressed by each tumor. Correlations between clinical aspects and molecular characteristics of tumors are of particular importance in the management of such a case. The study examined the impact of breast cancer molecular subtypes on therapeutic management for a group of 438 patients treated on the Oncology Department of the Bucharest University Emergency Hospital during 2007-2017.
Databáze: OpenAIRE