ARE TUMORAL MARKERS PREDICTIVE FACTORS FOR MOLECULAR SUBTYPES IN BREAST CANCER?
Autor: | V. Munteanu, Monica Cirstoiu, Georgiana Radu |
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Rok vydání: | 2019 |
Předmět: | |
Zdroj: | Journal of Surgical Sciences. 5:189-194 |
ISSN: | 2457-5364 2360-3038 |
Popis: | Breast cancer kills more women annually than any other type of neoplasm. Even though he has shown a particular interest in the medical body since ancient times, the very heterogeneous nature of the tumors and their versatility have made it difficult to find a diagnostic and therapeutic consensus that fully characterizes this pathology and describes its evolution. Immunohistochemical methods manage to outline a gene-molecular profile depending on the biomarkers expressed by each tumor. Correlations between clinical aspects and molecular characteristics of tumors are of particular importance in the management of such a case. The study examined the impact of breast cancer molecular subtypes on therapeutic management for a group of 438 patients treated on the Oncology Department of the Bucharest University Emergency Hospital during 2007-2017. |
Databáze: | OpenAIRE |
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