Immunothérapies innovantes des maladies allergiques respiratoires
| Autor: | Pascal Demoly, Anca M. Chiriac, Michel Fb |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Allergen immunotherapy Allergy business.industry medicine.medical_treatment General Medicine Atopic dermatitis Disease Immunotherapy medicine.disease medicine.disease_cause respiratory tract diseases 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Allergen 030228 respiratory system Immunology Medicine business Desensitization (medicine) Asthma |
| Zdroj: | Bulletin de l'Académie Nationale de Médecine. 200:545-559 |
| ISSN: | 0001-4079 |
| DOI: | 10.1016/s0001-4079(19)30731-9 |
| Popis: | Allergen immunotherapy (AIT) is an effective method in the treatment of respiratory allergic diseases (asthma, rhinitis and conjunctivitis). In addition to reducing symptoms, AIT can alter the course of allergic disease and remains efficient long after it has been discontinued by inducing specific tolerance to the allergen. In current clinical practice, immunotherapy is administered by subcutaneous or sublingual routes. The duration of efficacy is 7 to 12 years. It can prevent the development of both asthma and sensitization to new allergens. Despite recent progresses, other approaches are needed, especially for allergies (atopic dermatitis, food allergies). The new AIT improvement approaches involve the use of adjuvants or recombinant allergies, peptides and new routes of administration. |
| Databáze: | OpenAIRE |
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