172. Predictors of cardiac dose reduction achieved with deep inspiration breath hold technique over free breathing technique in left breast radiotherapy
| Autor: | M. Maddalo, G. Benecchi, C. Grondelli, E. Calabri, R. Rossi, P. Losardo, M.L. Bergamini, C. Dell’Anna, G. Ceccon, S. Nurmahomed, S. Gianni, M. Manicone, S. Andreani, F. Ghetti, F. Salaroli, C. Ghetti, N. D’Abbiero |
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| Rok vydání: | 2018 |
| Předmět: |
business.industry
medicine.medical_treatment Biophysics General Physics and Astronomy General Medicine Dose distribution Heart position Radiation therapy Left breast Heart size Medicine Radiology Nuclear Medicine and imaging Dose reduction business Nuclear medicine Free breathing Deep inspiration breath-hold |
| Zdroj: | Physica Medica. 56:169-170 |
| ISSN: | 1120-1797 |
| DOI: | 10.1016/j.ejmp.2018.04.183 |
| Popis: | Purpose Deep inspiration breath-hold (DIBH) has been routinely applied in left breast radiotherapy to reduce cardiac exposure. The purpose of this study was to compare deep inspiration breath hold and free breathing techniques (FB) in terms of heart and left-lung doses and to determine possible predictors of the dose reduction achieved with DIBH ( Δ DBH-FB). Methods Ten patients with left breast cancer have been treated with postoperative radiotherapy in Parma Hospital. For each patient both the FB and the DIBH planning CT were acquired. 3DCRT treatment plans using tangential field-in-field beams were developed for both FB and DIBH. FB and DIBH dose distributions were compared in terms of Dmean, V5Gy, V20Gy, V30Gy of the heart and V5Gy, V20Gy of the left-lung. Many geometric/anatomical parameters were measured in the FB condition: heart and left-lung volumes (Vheart, Vlung-L), maximum thickness of the same organs inside the tangential fields (dheart, dlung-L), axial and para-sagittal cardiac contact distances (CCDax, CCDps), maximum tangential distance between beam-entrance and beam-exit (dentrance-exit), maximum anteroposterior diameter of the chest. Results DIBH plans showed a significant reduction of Dmean (−60.9%), V5Gy (−82.5%), V20Gy (−93.6%) and (−95.8%) of the heart (p Δ DBH-FB were: Vheart (0.041 Conclusions This study confirmed how DIBH for left breast cancer treatment can decrease cardiac dose. The benefit of DIBH over FB strictly depends on chest shape, heart size and heart position. However, most of the parameters showed a weak correlation with Δ DBH-FB, so they cannot be used to effectively predict Δ DBH-FB. Only dheart seems to be a good predictor of Δ DBH-FB, but more cases must be included to confirm/reject these findings. |
| Databáze: | OpenAIRE |
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