Furosemide Adducts with Hexamethylenetetramine, Amantadine, and Isoniazid: A Structural Case That Demonstrates the Effect of Carboxylic Acid Dimer and Sulfonic Acid Dimer on the Solubility
Autor: | Dandan Huang, Zhengzheng Zhou, Jia-You Liu, Yanhui Wu, Fang Guo, Zhishan Liang, Yang Han, Hong-yu Guan |
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Rok vydání: | 2020 |
Předmět: |
chemistry.chemical_classification
010405 organic chemistry Carboxylic acid Dimer Amantadine Furosemide General Chemistry Sulfonic acid 010402 general chemistry Condensed Matter Physics 01 natural sciences Medicinal chemistry eye diseases 0104 chemical sciences Adduct chemistry.chemical_compound chemistry medicine General Materials Science Solubility Hexamethylenetetramine medicine.drug |
Zdroj: | Crystal Growth & Design. 20:4395-4401 |
ISSN: | 1528-7505 1528-7483 |
DOI: | 10.1021/acs.cgd.0c00187 |
Popis: | Furosemide, abbreviated as FS, is a loop diuretic drug with low solubility and permeability. Herein, three adducts derived from FS and hexamethylenetetramine (HTEM), amantadine (AMD) and isonicotin... |
Databáze: | OpenAIRE |
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