Furosemide Adducts with Hexamethylenetetramine, Amantadine, and Isoniazid: A Structural Case That Demonstrates the Effect of Carboxylic Acid Dimer and Sulfonic Acid Dimer on the Solubility

Autor: Dandan Huang, Zhengzheng Zhou, Jia-You Liu, Yanhui Wu, Fang Guo, Zhishan Liang, Yang Han, Hong-yu Guan
Rok vydání: 2020
Předmět:
Zdroj: Crystal Growth & Design. 20:4395-4401
ISSN: 1528-7505
1528-7483
DOI: 10.1021/acs.cgd.0c00187
Popis: Furosemide, abbreviated as FS, is a loop diuretic drug with low solubility and permeability. Herein, three adducts derived from FS and hexamethylenetetramine (HTEM), amantadine (AMD) and isonicotin...
Databáze: OpenAIRE