Somatomedin-C in Active and Successfully Treated Acromegaly
| Autor: | G. Knappe, V. Hesse, W. Rohde, Helga Gerl, G. Jahreis |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Chemotherapy Diagnostic methods business.industry Endocrinology Diabetes and Metabolism medicine.medical_treatment General Medicine medicine.disease Somatomedin Growth hormone secretion Elevated serum Endocrinology Internal medicine Acromegaly Internal Medicine medicine business Normal range |
| Zdroj: | Experimental and Clinical Endocrinology & Diabetes. 91:1-6 |
| ISSN: | 1439-3646 0947-7349 |
| Popis: | Sm-C concentrations in serum were found significantly different in either active acromegaly or following successful treatment with pituitary adenomectomy. Although after normalization of serum GH the Sm-C levels sometimes exceeded the normal range no overlap was found between both groups. Exceptionally two acromegalic patients showed elevated Sm-C levels in spite of normal GH values. Likewise, a high Sm-C concentration was found in one patient suspective of ectopic GH secretion with only moderately elevated serum GH. Sm-C determinations are judged as a good adjunct to usual diagnostic methods which in special cases of acromegaly can be even superior to measurements of serum GH. |
| Databáze: | OpenAIRE |
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