Chemical and biological studies on charge-transfer complexes of cimetidine with various electron acceptors
| Autor: | Sabry A. El-Korashy, Said M. Teleb, Mahmoud M. A. Ali, Akmal S. Gaballa |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Organic Chemistry Inorganic chemistry Ionic bonding Picric acid Electron acceptor Tetracyanoethylene 010402 general chemistry 01 natural sciences Acceptor 0104 chemical sciences Analytical Chemistry Inorganic Chemistry chemistry.chemical_compound chemistry Chloranilic acid Proton NMR Spectroscopy |
| Zdroj: | Journal of Molecular Structure. 1202:127256 |
| ISSN: | 0022-2860 |
| DOI: | 10.1016/j.molstruc.2019.127256 |
| Popis: | Interaction of Cimetidine drug (CIM) with π-acceptors as Tetracyanoethylene (TCNE) and 7,7′,8,8′-Tetracyanoquinodimethane (TCNQ), chloranilic acid (H2CA) picric acid (HPA) resulted through the initial formation of ionic intermediate to charge transfer (CT) complex which detected by spectroscopic studies. The molar ratio was found to be 1:1 between cimetidine drug and different acceptor. The formed CT complexes have been characterized using various techniques such as the elemental analyses, UV–Vis., IR, and 1H NMR spectra, and thermal analyses (TG, DTG). The antibacterial activity of the complexes were estimated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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