Analogs of oxytocin with L- and D-pentafluorophenylalanines in the second position

Autor: O. A. Kaurov, M. P. Smirnova
Rok vydání: 1977
Předmět:
Zdroj: Chemistry of Natural Compounds. 13:332-336
ISSN: 1573-8388
0009-3130
DOI: 10.1007/bf00573555
Popis: 1. The separation of pentafluorophenylalanine into optical antipodes has been effected. 2. Two new analogs of oxytocin — [2-L-pentafluorophenylalanine]oxytocin and [2-D-pentafluorophenylalanine]oxytocin — have been synthesized and their uterotonic activities have been studied. 3. It has been shown that donor — acceptor interaction plays a fundamental role in the stimulation of the biological effect.
Databáze: OpenAIRE