Analogs of oxytocin with L- and D-pentafluorophenylalanines in the second position
Autor: | O. A. Kaurov, M. P. Smirnova |
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Rok vydání: | 1977 |
Předmět: | |
Zdroj: | Chemistry of Natural Compounds. 13:332-336 |
ISSN: | 1573-8388 0009-3130 |
DOI: | 10.1007/bf00573555 |
Popis: | 1. The separation of pentafluorophenylalanine into optical antipodes has been effected. 2. Two new analogs of oxytocin — [2-L-pentafluorophenylalanine]oxytocin and [2-D-pentafluorophenylalanine]oxytocin — have been synthesized and their uterotonic activities have been studied. 3. It has been shown that donor — acceptor interaction plays a fundamental role in the stimulation of the biological effect. |
Databáze: | OpenAIRE |
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