Acantholytic dyskeratotic epidermal nevus: a rare histopathologic feature
| Autor: | I. Thibaut, J. Mazereeuw-Hautier, J. L. Bonafé |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Pathology Acantholytic dyskeratotic epidermal nevus Histology integumentary system business.industry Acantholysis Hyperkeratosis Acanthosis Dermatology Papillomatosis medicine.disease Epidermal nevus syndrome Dyskeratosis Pathology and Forensic Medicine medicine.anatomical_structure medicine Epidermis medicine.symptom business |
| Zdroj: | Journal of Cutaneous Pathology. 29:52-54 |
| ISSN: | 0303-6987 |
| DOI: | 10.1034/j.1600-0560.2002.290110.x |
| Popis: | Background: Epidermal nevus is a congenital malformation of the epidermis consisting of verrucoid scaly plaques on the skin, often in a linear fashion. Different histologic features have been seen and, at times, acantholytic dyskeratosis has been observed. We report a new case of acantholytic dyskeratotic epidermal nevus. Case report: A 3-year-old girl presented, since birth, asymptomatic keratotic scaly lesions on the left hemithorax and left arm that followed Blaschko's lines. Histology: Biopsies revealed acanthosis, papillomatosis, hyperkeratosis and focal areas of suprabasal clefting with acantholysis, as well as individual dyskeratotic cells (corps ronds et grains) in the upper layers of the epidermis. In the literature, this histologic feature has been reported twice. Generalized or localized Darier's disease are well-established clinical entities with characteristic histologic features of acantholytic dyskeratosis. Because of the linear clinical appearance and the onset at birth or early chilhood, the lesions should be regarded as epidermal nevi and not linear Darier's disease. Conclusion: We report here an additional case of dyskeratotic epidermal nevus, which is a rare histopathologic feature. |
| Databáze: | OpenAIRE |
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