IN VITRO CHARACTERIZATION OF HYDROXYAPATITE-BASED BIOMATERIALS, USING MESENCHYMAL STEM CELL CULTURES FROM HUMAN BONE MARROW

Autor:	Johny Neamtu, Cristina Teisanu, Livia Elena Sima, Oana Gingu, Gabriela Sima, Renata Maria Varut
Rok vydání:	2020
Předmět:	Materials science 0206 medical engineering Mesenchymal stem cell Human bone 02 engineering and technology 021001 nanoscience & nanotechnology 0210 nano-technology 020601 biomedical engineering In vitro Cell biology
Zdroj:	Journal of Science and Arts. 20:969-976
ISSN:	2068-3049 1844-9581
Popis:	There is considerable interest in the discovery of biomimetic materials that improve cell adhesion and reduce the time of bone integration of implants. In vitro bone cells biocompatibility was performed for the two types of biocomposites hydroxyapatite-titanium (HApTi) and hydroxyapatite-titanium with added calcium fructoborate (HApTiCaFb). In order to investigate the potential cytotoxicity of biomaterials, cell adhesion, proliferation, and osteogenic differentiation, human mesenchymal stem cells (MSCs) were used. Regarding the in vitro biocompatibility, a slight improvement in the phenotype was observed for the samples to which CaFb was added.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2192d17e1b246e1c7207a2f880faa03b https://doi.org/10.46939/j.sci.arts-20.4-b02 Zobrazit plný text záznamu