ChemInform Abstract: Isoxazole to Oxazole: A Mild and Unexpected Transformation
Autor: | Mark R. J. Elsegood, Romain Marty, Alexander Chatterley, Raymond C. F. Jones, W. Martin Owton |
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Rok vydání: | 2015 |
Předmět: | |
Zdroj: | ChemInform. 46 |
ISSN: | 0931-7597 |
Popis: | 3-Aryltetrahydrobenzisoxazoles prepared en route to the coleophomone natural products and analogues, were found to undergo a remarkable base-mediated rearrangement to 2-aryltetrahydrobenzoxazoles. The scope of this unprecedented, facile transformation was probed: a range of analogues was produced, a mechanism proposed, and an application demonstrated by synthesis of a known herbicidal compound. |
Databáze: | OpenAIRE |
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