ChemInform Abstract: Isoxazole to Oxazole: A Mild and Unexpected Transformation

Autor: Mark R. J. Elsegood, Romain Marty, Alexander Chatterley, Raymond C. F. Jones, W. Martin Owton
Rok vydání: 2015
Předmět:
Zdroj: ChemInform. 46
ISSN: 0931-7597
Popis: 3-Aryltetrahydrobenzisoxazoles prepared en route to the coleophomone natural products and analogues, were found to undergo a remarkable base-mediated rearrangement to 2-aryltetrahydrobenzoxazoles. The scope of this unprecedented, facile transformation was probed: a range of analogues was produced, a mechanism proposed, and an application demonstrated by synthesis of a known herbicidal compound.
Databáze: OpenAIRE