Calcium phosphate–calcium titanate composite coatings for orthopedic applications
| Autor: | J. Esguerra Arce, Y. Aguilar, Luis Yate, Sergio Moya, A. Esguerra Arce, Oscar Gutiérrez, C. Rincón |
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| Rok vydání: | 2016 |
| Předmět: |
Materials science
Simulated body fluid Composite number chemistry.chemical_element 02 engineering and technology Calcium engineering.material 010402 general chemistry 01 natural sciences Apatite chemistry.chemical_compound Coating Materials Chemistry Process Chemistry and Technology Metallurgy Sputter deposition Nanoindentation 021001 nanoscience & nanotechnology 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Calcium titanate chemistry Chemical engineering visual_art Ceramics and Composites visual_art.visual_art_medium engineering 0210 nano-technology |
| Zdroj: | Ceramics International. 42:10322-10331 |
| ISSN: | 0272-8842 |
| DOI: | 10.1016/j.ceramint.2016.02.177 |
| Popis: | Novel bioactive calcium titanate–tricalcium phosphate–tetracalcium phosphate composite coatings were developed. Powder mixtures of hydroxyapatite and 25, 50 and 75 vol% of calcium titanate were uniaxially pressed and sintered at 1100–1200 °C for 4 h. After heat treatment, the composites, which consisted of calcium titanate and oxyhydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2−2 x O x □ x ), were evaporated by magnetron sputtering to coat an AISI 304/Ti buffer layer substrate. Calcium phosphate (CP) and calcium titanate (CT) coatings were also produced for comparison. The surface topography of the composite coatings was observed by SEM and AFM. Their structure and composition were evaluated by XRD, FTIR and XPS, and the re-assembly process of the atoms from composite targets to the coatings was emphasized. Nanoindentation experiments were carried out to measure the hardness. Coated samples were immersed in a simulated body fluid (SBF) for 30 days under physiological conditions of pH and temperature for the in-vitro bioactivity assessment. Finally, because the coatings are proposed for orthopedic applications, the cytotoxicity of the coatings was examined with human osteoblasts. It was found that calcium titanate coating is harder than the calcium phosphate coating, the 75–25 composite coatings fit a rule of mixture of hardness, and the rougher coatings contained a larger amount of nano-scale precipitated apatite. Furthermore, all the coatings were not cytotoxic. The results indicate that 75%CP–25%CT coating is a potential material for bone tissue replacement and regeneration. |
| Databáze: | OpenAIRE |
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