Synthesis of S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole
Autor: | O. M. Bondareva, V. E. Naidenov, Z. I. Kuvaeva, L. Yu. Tychinskaya, D. V. Lopatik |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Proceedings of the National Academy of Sciences of Belarus, Chemical Series. 57:294-299 |
ISSN: | 2524-2342 1561-8331 |
DOI: | 10.29235/1561-8331-2021-57-3-294-299 |
Popis: | Condensed indole derivatives of the 1,2,4-triazino[5,6-b]indole group show high biological activity and are of interest for the development of pharmaceuticals that have antihypoxic and antisurditant effects. By S-aminoalkylation reactions on a thione group, S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole-3-thione that were subject to hydrobromination in order to obtain the form of hydrobromides were synthesized, isolated and characterized. |
Databáze: | OpenAIRE |
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