Synthesis of S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole

Autor: O. M. Bondareva, V. E. Naidenov, Z. I. Kuvaeva, L. Yu. Tychinskaya, D. V. Lopatik
Rok vydání: 2021
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of Belarus, Chemical Series. 57:294-299
ISSN: 2524-2342
1561-8331
DOI: 10.29235/1561-8331-2021-57-3-294-299
Popis: Condensed indole derivatives of the 1,2,4-triazino[5,6-b]indole group show high biological activity and are of interest for the development of pharmaceuticals that have antihypoxic and antisurditant effects. By S-aminoalkylation reactions on a thione group, S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole-3-thione that were subject to hydrobromination in order to obtain the form of hydrobromides were synthesized, isolated and characterized.
Databáze: OpenAIRE