| Autor: |
Paola Erba, L Ceriani, Luca Giovanella, S Garancini, Patrizia Vio |
| Rok vydání: |
1999 |
| Předmět: |
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| Zdroj: |
Radioactive Isotopes in Clinical Medicine and Research XXIII ISBN: 9783034897723 |
| DOI: |
10.1007/978-3-0348-8782-3_85 |
| Popis: |
Total PSA assay is a well established procedure for biochemical evaluation and management of PCa which usefulness in its diagnosis is limited by its weak specificity with regard to BPH. Recently the assay of Free-PSA and the calculation of Free/Total-PSA Ratio has been suggested to improve the specificity of PSA in the range of concentrations between 2.5 and 20 ng/mL. We evaluated the diagnostic performance of PSA-Ratio among untreated patients with PSA levels ranging from 2.5 to 20 ng/mL and histological diagnosis of PCa or BPH. As the ROC curves analysis showed PSA-Ratio is the better parameter to discriminate between PCa and BPH: PSA-Ratio could be employed to enhance the diagnostic performance of PSA alone in PCa diagnosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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