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Objective: Treatment decisional preferences impact breast cancer patients? health-related quality oflife (HRQoL) and may relate to psychological variables, although many aspects of this relationshipremain unknown. This prospective study aimed to assess psychological correlates of treatmentdecisional preferences and predictors of HRQoL in women with early non-metastatic breast cancer.Methods: Of the 124 women initially assessed for anxiety (Spielberger?s State?Trait AnxietyInventory) and depressive (Center for Epidemiologic Studies-Depression (CES-D)) symptoms, HRQoL(WHOQOL-BREF), and defense mechanisms (Life Style Index), 82 (66.1%) completed the 1-year followup.Mean age was 54.6 years (SD= 9.76), andmean disease duration was 19.4months (SD= 25.55); 19.5%had stage I, 63.4% stage II and 17.1% stage III disease. The predictive power and moderator effects ofpsychological variables were tested using multiple and hierarchical regression models.Results: Depressive symptoms and physical HRQoL improved significantly, state anxiety and mentaland environment HRQoL remained stable, and social relations HRQoL deteriorated over the 1-yearperiod. Older age (p = 0.021) and higher scores in repression defense (p = 0.044) were independentlyassociated with passive decisional preferences. Earlier stage of cancer (p = 0.043), lower state anxiety(p = 0.039), lower repression scores (p = 0.021) and improvement in depressive symptoms (p |
