Sequential simplex optimization in a constrained simplex mixture space in liquid chromatography

Autor:	Stanley N. Deming, Hui-Li Chang, Iphigenia Leonidou, John A. Palasota, Josephine M. Palasota
Rok vydání:	1992
Předmět:	Simplex Chromatography Analytical chemistry Chromatographic response function Biochemistry Toluene Analytical Chemistry chemistry.chemical_compound chemistry Simplex algorithm Phase (matter) Environmental Chemistry Phenol Sample preparation Constant (mathematics) Spectroscopy
Zdroj:	Analytica Chimica Acta. 270:101-106
ISSN:	0003-2670
DOI:	10.1016/0003-2670(92)80096-p
Popis:	The sequential simplex method is used in a constrained simplex mixture space to optimize the liquid chromatographic separation of five neutral organic solutes: uracil, phenol, acetophonenone, methylbenzoate, and toluene. The mobile phase composition is varied while column temperature, mobile phase flow-rate, and sample concentration are held constant. The chromatographic response function and the total analysis time are used in an overall desirability function to direct the progress of the sequential simplex optimization.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::214504dec098f298ca4ade88da2c4573 https://doi.org/10.1016/0003-2670(92)80096-p Zobrazit plný text záznamu