Long-term Storage Stability Assessment of Omega-3-Fatty Acid Emulsified Formulation Containing Micronutrients

Autor: Anand A. Zanwar, Pramod D. Farde, Yogesh S. Badhe, Amit A. Jagtap, Mahabaleshwar V. Hegde
Rok vydání: 2021
Předmět:
Zdroj: Journal of Pharmaceutical Innovation. 17:1126-1135
ISSN: 1939-8042
1872-5120
Popis: Role of omega-3 fatty acid (ω-3 FA) in human health and negative impact of altered omega-6 to 3 ratio is well documented. Hence, food fortification with ω-3 FA is need of the day. Functional foods containing ω-3 FA are gaining a lot of importance. However, long-term stability of ω-3 FA is a major obstacle with respect to the consumer acceptability and industrial exploitation of such functional food. The present study was a systematic attempt to assess the stability and acceptability of ω-3 FA emulsified formulation. Formulation was developed using flax oil with micronutrients and antioxidants at different doses (2–5 g/serve). The formulations were evaluated for long-term storage stability using various parameters such as oxidative stability, fatty acid analysis, optical microscopy, particle size analysis and zeta potential evaluation, colour analysis, and cryo-scanning electron microscopic analysis. Finally, the formulation was subjected for sensory evaluation using a 9-point hedonic scale to understand the overall acceptability of the formulation. There were significant alterations in oxidative stability parameters (p
Databáze: OpenAIRE
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