Impact of troponin 1 on long-term mortality after emergency orthopaedic surgery in older patients
| Autor: | Que T. Lam, Rabindra N. Sinnappu, Wen Kwang Lim, Carol P Chong, Julie E. Ryan |
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| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
biology Proportional hazards model business.industry Atrial fibrillation Retrospective cohort study Odds ratio medicine.disease Troponin Asymptomatic Internal medicine Troponin I Internal Medicine medicine biology.protein Cardiology medicine.symptom business Prospective cohort study |
| Zdroj: | Internal Medicine Journal. 40:751-756 |
| ISSN: | 1444-0903 |
| DOI: | 10.1111/j.1445-5994.2009.02063.x |
| Popis: | Objectives: To determine the association between post-operative troponin rises and longer term (2-year) mortality after emergency orthopaedic surgery in patients over 60 years of age. Methods: One hundred and two patients were recruited in 2006 and had inpatient troponin 1 measurements. These patients were followed up by a telephone call annually for complications. Results: At 2 years, 29.4% (30/102) of patients had died. Twenty-five patients (25/54 or 49.3%) with a troponin rise were dead at 2 years compared with five patients without a troponin rise (5/48 or 10.4%), which was significantly different P 0.1 µg/L) were more likely to be dead at 2 years compared with those with a lower level of troponin. However, when adjusted for other comorbidities the association between troponin elevation and death at 2 years did not persist. Using Cox regression multivariate analysis, only one factor, sustaining an in-hospital cardiac event odds ratio 4.3 (95% confidence interval 1.8–10.3, P = 0.001), was associated with 2 years all-cause mortality . Furthermore, patients who sustained a symptomatic troponin rise (P |
| Databáze: | OpenAIRE |
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