Repeat symptomatic Neisseria gonorrhoeae infections among men who have sex with men in Bangkok, Thailand, 2006–2016
| Autor: | Chaiwat Ungsedhapand, Wichuda Sukwicha, Anupong Chitwarakorn, Timothy H. Holtz, Philip A. Mock, Sarika Pattanasin, Pachara Sirivongrangson, Eileen F. Dunne, Wannee Chonwattana, Jaray Tongtoyai |
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| Rok vydání: | 2020 |
| Předmět: |
Neisseria gonorrhoeae Infections
medicine.medical_specialty business.industry Incidence (epidemiology) Public Health Environmental and Occupational Health Dermatology medicine.disease_cause Men who have sex with men Infectious Diseases Internal medicine medicine Neisseria gonorrhoeae Pharmacology (medical) business Cohort study |
| Zdroj: | International Journal of STD & AIDS. 31:533-540 |
| ISSN: | 1758-1052 0956-4624 |
| DOI: | 10.1177/0956462420906763 |
| Popis: | We analyzed the incidence and predictors of symptomatic repeat Neisseria gonorrhoeae (NG) infection among men who have sex with men (MSM) enrolled in the Bangkok MSM Cohort Study. Thai MSM aged ≥18 years were enrolled during 2006–2010 and followed every four months. At baseline, participants were screened for rectal and urethral NG and Chlamydia trachomatis (CT) infections using nucleic acid amplification testing (NAAT), rectal and pharyngeal NG by culture, and pharyngeal CT by NAAT. During follow-up, symptomatic participants were tested for NG infection by NAAT and Gram stain of rectal or urethral specimens. Among 1464 participants without NG infection at the baseline visit and having at least one follow-up visit, 11.2% (164/1464) developed symptomatic NG infection, for a total of 251 infections. Symptomatic repeat NG infection occurred in 28.0% (46/164) of participants. The incidence rate was 3.9 cases per 100 person-years. Baseline predictors of repeat symptomatic NG were as follows: unknown human immunodeficiency virus (HIV) status despite history of HIV testing, previous sexually transmitted infection diagnosis by physician, insertive-only anal intercourse without a condom, amyl nitrate use at baseline, CT infection at baseline, age 18–24 years, and being a student; HIV infection at baseline or during the study period was also associated with repeat symptomatic NG infection. |
| Databáze: | OpenAIRE |
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