NRROS negatively regulates reactive oxygen species during host defence and autoimmunity

Autor:	Naruhisa Ota, Patricia A. Valdez, Tao Sai, Sascha Rutz, Robert Soriano, Andrew Sebrell, Ivan Peng, Jiabing Ding, Zora Modrusan, Patrick Caplazi, Celine Eidenschenk, Jason A. Hackney, Kit Wong, Wenjun Ouyang, Rongze Lu, Jason DeVoss, Rajkumar Noubade
Rok vydání:	2014
Předmět:	chemistry.chemical_classification Reactive oxygen species Multidisciplinary NADPH oxidase biology Endoplasmic reticulum Host defence medicine.disease_cause Autoimmunity Cell biology Membrane protein chemistry Biochemistry Tissue damage medicine biology.protein Oxidative stress
Zdroj:	Nature. 509:235-239
ISSN:	1476-4687 0028-0836
DOI:	10.1038/nature13152
Popis:	The leucine-rich repeat protein NRROS which resides in the endoplasmic reticulum regulates phagocytic NADPH oxidase, minimizing collateral tissue damage caused by reactive oxygen species during inflammatory processes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::20fc39e9808f14d7212d637fc16a0f50 https://doi.org/10.1038/nature13152 Zobrazit plný text záznamu Plný text ve formátu PDF