Cell adhesion study of the titanium alloys exposed to glow discharge

Autor: Satilmis Budak, Daryush Ila, B.H. Sen, V. Abidzina, I. Tereshko, F. Ozdal-Kurt, I Deliloğlu-Gürhan, Claudiu Muntele, I. Elkin
Rok vydání: 2007
Předmět:
Zdroj: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 261:624-626
ISSN: 0168-583X
DOI: 10.1016/j.nimb.2007.04.165
Popis: Titanium for biomedical application stems mainly from its advantageous bulk mechanical properties in combination with a high degree of biocompatibility that is largely attributable to their surface properties. This work is focused on the investigation of surface properties of treated titanium and cell adhesion to titanium treated in glow-discharge plasma. Pure titanium samples (grade 4) were exposed to low-energy ion irradiation in a specially constructed plasma generator, where materials were irradiated by ions of residual gases in vacuum. The ion energy was 1–10 keV. The irradiation dose was maintained at 10 17 ions cm −2 . The irradiation time varied from 5 to 60 min. Rutherford backscattering spectrometry (RBS) was used for surface studies. RBS showed the presence of iron on the titanium surface that occurred from the cathode of plasma generator. In vitro biocompatibility test have been carried out with model cell lines (L929 mouse fibroblasts) to demonstrate that low-energy ion irradiation can favorably influence the surface of titanium for biomedical application. Scanning electron microscopy (SEM) was the main tool to demonstrate the cell attachment properties.
Databáze: OpenAIRE