Crioglobulinemia tipo I de desenlace fatal
| Autor: | Magalys Vitiello, Francisco A. Kerdel, B. Echeverría, Adriana Abuchar |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Lymphoproliferative disorders Severe disease General Medicine Pathology study medicine.disease Cryoglobulinemia Dermatology Monoclonal gammopathy Unknown Significance hemic and lymphatic diseases Immunology medicine Plasmapheresis medicine.symptom business Vasculitis |
| Zdroj: | Actas Dermo-Sifiliográficas. 102:212-215 |
| ISSN: | 0001-7310 |
| DOI: | 10.1016/j.ad.2010.10.011 |
| Popis: | Type I Cryoglobulinemia With a Fatal Outcome Abstract Type I cryoglobulinemia, a condition associated with lymphoproliferative disorders, is caused by monoclonal immunoglobulins that precipitate at low temperatures. It mostly invol- ves the skin and pathology study shows no signs of vasculitis. Management is usually based on immunosuppressive drugs associated with plasmapheresis for severe disease. The use of rituxi- mab has recently been described for resistant cases. We present an unusual case of long-standing type I cryoglobulinemia associated with a monoclonal gammopathy of unknown significance. The patient developed extremely severe skin lesions with histological signs of vasculitis. The patient died due to the onset of noncutaneous manifestations of the cryoglobulinemia and complications of the immunosuppressive treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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