In vitroantibacterial activity and physicochemical properties of a crude methanol extract of the larvae of the blow flyLucilia cuprina
| Autor: | W. A. Nazni, S. B. Tan, H. L. Lee, Mohd Sofian-Azirun, C. H. Teh, A. Fairuz |
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| Rok vydání: | 2013 |
| Předmět: |
General Veterinary
biology fungi Pathogenic bacteria biology.organism_classification medicine.disease_cause Lucilia Microbiology Minimum inhibitory concentration Staphylococcus aureus Lucilia cuprina Insect Science medicine Parasitology Calliphoridae Antibacterial activity Ecology Evolution Behavior and Systematics Bacteria |
| Zdroj: | Medical and Veterinary Entomology. 27:414-420 |
| ISSN: | 0269-283X |
| Popis: | The emergence of multidrug-resistant bacterial strains has prompted the reintroduction of maggot therapy in the treatment of chronic, infected wounds. Many previous studies have demonstrated the potent antibacterial activity of larval excretions/secretions of the blowfly Lucilia sericata (Meigen) (Diptera:Calliphoridae) against bacteria. However, the antibacterial activity of its sibling species, Lucilia cuprina (Wiedemann) (Diptera:Calliphoridae) against a wide range of pathogenic bacteria has never been determined. The aim of this study was to develop a new procedure to produce whole body extract of larvae of L. cuprina via methanol extraction as well as to demonstrate the in vitro antibacterial activity of this extract against seven selected wound pathogens (Staphylococcus aureus, methicillin-resistant S. aureus, S. epidermidis, Streptococcus pyogenes, Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli). The turbidimetric assay demonstrated that L. cuprina larval extract was significantly potent against all bacteria tested (P |
| Databáze: | OpenAIRE |
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