High prevalence of hepatitis C virus infection in Airin district, Osaka, Japan: A hospital-based study of 1162 patients
| Autor: | Yasunori Yamaguchi, Tetsuya Tanigawa, Hiroki Sakaguchi, Kenji Watanabe, Akihiro Tamori, Hideki Fujii, Masaru Enomoto, Yasuhiro Fujiwara, Norifumi Kawada, Tetsuo Arakawa, Shigeyoshi Harihara, Takeyuki Monna |
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| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
education.field_of_study Hepatology biology business.industry Hepatitis C virus medicine.medical_treatment Population Hepatitis C Disease medicine.disease medicine.disease_cause Surgery Infectious Diseases Internal medicine Hepatocellular carcinoma Genotype medicine biology.protein Antibody Hepatectomy education business |
| Zdroj: | Hepatology Research. 41:731-737 |
| ISSN: | 1386-6346 |
| Popis: | Aim: The Airin district, located in Nishinari-ku, Osaka, is known as Japan's largest slum area, and has the largest concentration of day laborers in the country. We conducted a large hospital-based study to determine the prevalence of hepatitis C virus (HCV) infection in the district. Methods: The subjects were 1162 men (mean age, 57 ± 9 years) admitted to the Osaka Socio-Medical Center Hospital between April 2005 and March 2008. Their case records were retrospectively reviewed. Results: Anti-HCV antibodies were found in 218 (18.8%) patients; in contrast, only 24 (2.1%) patients had hepatitis B surface antigen. The prevalence of anti-HCV antibodies was 59% among the 122 patients admitted for liver diseases and 14% among the 1040 patients with other diseases. Among 927 patients with normal alanine aminotransferase levels (≤40 IU/L), 128 (13.8%) had anti-HCV antibodies. The prevalence of anti-HCV antibodies increased with age significantly (P |
| Databáze: | OpenAIRE |
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