Stereoselective Bioreduction of Hexan-2-one into (2S)-(+)-Hexan-2-ol

Autor:	A. R. Chanysheva, E. A. Sheiko, Vladimir V. Zorin
Rok vydání:	2018
Předmět:	chemistry.chemical_compound Ethanol 010405 organic chemistry Chemistry Reducing agent Yield (chemistry) Enantioselective synthesis Organic chemistry Stereoselectivity General Chemistry 010402 general chemistry 01 natural sciences 0104 chemical sciences
Zdroj:	Russian Journal of General Chemistry. 88:2934-2936
ISSN:	1608-3350 1070-3632
Popis:	A method for the synthesis of (2S)-(+)-hexan-2-ol, the precursor of a series of drugs, by the enantioselective bioreduction of the prochiral hexan-2-one is proposed. The use of various exogenous reducing agents (isopropanol, ethanol, and glucose) for increasing the yield of the target (2S)-(+)-hexan-2-ol and the enantioselectivity of the bioreduction of hexane-2-one are investigated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::20cf47d3bfc4418d83c5b0d8ed645759 https://doi.org/10.1134/s1070363218130170 Zobrazit plný text záznamu Plný text ve formátu PDF