Potential histopathological and molecular changes in rat vas deferens inhaled byBoswellia papyriferaandBoswellia carterii
| Autor: | Afrah F. Alkhuriji, Mukhtar Ahmed, Mukhtar Ahmed G. Ghodesawar, Daoud Ali, Suliman Y. Al Omar, R.H. Aladakatti, Shaban R.M. Sayed |
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| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty biology Health Toxicology and Mutagenesis Vas deferens Motility Fructose biology.organism_classification Pollution Epithelium Andrology Contractility chemistry.chemical_compound medicine.anatomical_structure chemistry Cytoplasm medicine Ultrastructure Environmental Chemistry Boswellia papyrifera |
| Zdroj: | Toxicological & Environmental Chemistry. :1-14 |
| ISSN: | 1029-0486 0277-2248 |
| DOI: | 10.1080/02772248.2014.982937 |
| Popis: | Boswellia papyrifera and Boswellia carterii released from smoke contaminate indoor environment and consequently adversely affect humans as evidenced by respiratory disturbances. The aim of this study was to determine the effects of these plants on pathological and biochemical changes in vas deferens of albino rats. Animals were administered 4 g/kg body weight B. papyrifera and B. carterii daily for 120 days along with controls. Significant changes were observed in epithelial cell types and some cells showed signs of degeneration. The ultrastructural studies revealed marked changes in cytoplasmic organelles. Microvilli were missing and lysosomes were found in the cytoplasm. In addition, all treated groups plasma fructose and other biochemical parameters were decreased indicating reduced energy necessary for motility and contractility of spermatozoa. Many spermatozoa were disorganized and agglomerated. Data suggest that smoke from these plants adversely affects vas deferens. |
| Databáze: | OpenAIRE |
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