Properties of the slow excitatory postsynaptic potential in mammalian sympathetic ganglion cells
| Autor: | Skok Vi, Ivanov AIa |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Superior cervical sympathetic ganglion
Carbachol Physiology musculoskeletal neural and ocular physiology General Neuroscience Depolarization Hyperpolarization (biology) Biology nervous system Muscarinic acetylcholine receptor medicine Excitatory postsynaptic potential Biophysics Reversal potential Neuroscience Acetylcholine medicine.drug |
| Zdroj: | Neurophysiology. 13:278-284 |
| ISSN: | 1573-9007 0090-2977 |
| DOI: | 10.1007/bf01058663 |
| Popis: | Two types of slow excitatory postsynaptic potentials (EPSPs) with different properties were found in neurons of the rabbit superior cervical sympathetic ganglion. In our group of neurons slow EPSPs increased during artificial hyperpolarization and decreased during depolarization of the membrane. The input resistance of the cells fell or remained unchanged during the development of slow EPSPs. In the second group of cells slow EPSPs increased during depolarization and decreased during hyperpolarization. The reversal potential of these responses, determined by extrapolation, was −78.9±3.6 mV. Depolarization responses to activation of muscarinic cholinergic receptors by acetylcholine or carbachol developed in 53% of neurons with an increase in input resistance and had a reversal potential of −83.2±6.7 mV. It is suggested that in cells of the first group the ionic mechanism of the slow EPSPs is similar to that of the fast EPSPs, whereas in cells of the second group its main component is a decrease in the potassium conductance of the membrane. |
| Databáze: | OpenAIRE |
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