АКТИВНОСТЬ НЕЙРОНОВ НИЖНЕГО ВЕСТИБУЛЯРНОГО ЯДРА ПРИ СТИМУЛЯЦИИ ПАРАВЕНТРИКУЛЯРНОГО И СУПРАОПТИЧЕСКОГО ЯДЕР ГИПОТАЛАМУСА В УСЛОВИЯХ УНИЛАТЕРАЛЬНОЙ ЛАБИРИНТЭКТОМИИ, СОЧЕТАННОЙ С ВИБРАЦИОННЫМ ВОЗДЕЙСТВИЕМ
| Autor: | Sarkisyan S, H., Chavushyan V, A., Meliksetyan I, B., Minasyan S, M., Sarkissian J, S. . |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
single neuronal activity
inferior vestibular nucleus тетаническая стимуляция nervous system одиночная нейрональная активность paraventricular and supraoptic nuclei of hypothalamus паравентрикулярное и супраоптическое ядра гипоталамуса unilateral labyrinthectomy вибрационное воздействие унилатеральная лабиринтэктомия tetanic stimulation нижнее вестибулярное ядро vibration exposure |
| DOI: | 10.18454/asy.2012.18.672 |
| Popis: | We have performed the programmed analysis of changes of frequency of single neuronal spike activity flow of inferior vestibular nucleus (IVN) of rats, evoked by high frequency stimulation (HFS) of paraventricular (PVN) and supraoptic nuclei (SON) of hypothalamus in conditions of unilateral labyrinthectomy (UL) combined with multi-day vibration exposure (VE). In neurons of the uninjured side of the IVN HFS PVN and SON dominate inhibitory responses (84.50% and 75.80%, respectively), on the affected side also predominate inhibitory responses (55.10% and 48.80% respectively), along with excitatory (28,20% and 43.50% respectively). It is assumed that the dominance of GABAergic effects contribute to vestibular compensation after UL. The results of the morphological and histochemical study confirm the neuroprotective role of VE in condition of UL. |
| Databáze: | OpenAIRE |
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