Determination of baseline 'Widal titre' amongst apparently healthy individuals at tertiary health care center

Autor: Nimisha Shethwala, Amar R. Shah, Himanshu S. Khatri
Rok vydání: 2019
Předmět:
Zdroj: Indian Journal of Microbiology Research. 6:190-193
ISSN: 2394-5478
2394-546X
Popis: Enteric fever is en demic in all parts of India The term, ‘enteric fever ’ includes typhoid fever which is caused by S.typhi and paratyphoid fever which is caused by S. paratyphi A, B and C. However, in countries like India, isolation of organism is often jeopardized by lack of facilities or inadequate and/or improper antibiotic use prior to culture and also, culture positive cases are very less and time consuming. Laboratory diagnosis of enteric fever still relies on serological tests such as the Widal test [2;3] . The test becomes reliable if at least two properly staged tests show about a four -fold rise in antibody levels [4] . Often specific antibiotics are administered based on the single Widal test. Interpretation of a single Widal test result needs to be based on the average baseline antibody titre which is seen among healthy in dividuals in the local area. So we aimed to find out the baseline antibody titer in our area. A single blood sample is collected from the healthy blood donors coming to the blood bank. Widal test is performed by tube agglutina tion method. The baseline titre found in our area for TO, TH, AH, and BH are1:40 1:4 0, 1:40 & 1:2 0 respectively. Keywords: Baseline titre enteric fever, Widal test, Healthy individuals
Databáze: OpenAIRE