| Autor: |
Neal Duggal, Milo Engoren, Scott M Chadderdon, Evelio Rodriguez, M. Andrew Morse, Mani A Vannan, Pradeep Yadav, Michael Morcos, Flora Li, Mark Reisman, Enrique Garcia-Sayan, Deepa Raghunathan, Nishtha Sodhi, Paul Sorajja, lily chen, Jason H Rogers, Marcella Calfon Press, Christopher Kovach, Edward A Gill, Firas Zahr, Stanley Chetcuti, Yuan Yuan, Graciela Mentz, D. Scott Lim, Gorav Ailawadi |
| Rok vydání: |
2023 |
| DOI: |
10.1101/2023.03.16.23287387 |
| Popis: |
BACKGROUND The association, if any, between the effective regurgitant orifice (EROA) to left ventricular end-diastolic volume (LVEDV) ratio and 1-year mortality is controversial in patients undergoing mitral transcatheter edge-to-edge repair (m-TEER) with the MitraClip™ system. The objective is to determine the association between EROA/LVEDV and 1-year mortality among patients undergoing m-TEER with MitraClip™. METHODS In patients with severe secondary (functional) mitral regurgitation (MR), we analyzed registry data from 11 centers using generalized linear models with the generalized estimating equations approach. RESULTS We studied 525 patients with secondary MR who underwent m-TEER in 11 centers. Most patients were male (63%) and were NYHA class III (61%) or IV (21%). MR was caused by ischemic cardiomyopathy in 51% of patients. EROA/LVEDV values varied widely with median=0.19 mm2/mL, interquartile range [0.12,0.28] mm2/mL, and 187 (36%) patients had values |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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