Prevalence of Helicobacter pylori infection, its correlation with gastroduodenal diseases and the incidence of gastric cancer in Nepal

Autor:	Vijay M Alurkar, SC Kohli, Umid Kumar Shrestha, Subash Sapkota, Arnab Ghosh
Rok vydání:	2013
Předmět:	medicine.medical_specialty business.industry Incidence (epidemiology) Peptic Cancer Odds ratio medicine.disease Gastroenterology digestive system diseases Confidence interval Duodenitis Gastric Polyp Internal medicine medicine Gastritis medicine.symptom business
Zdroj:	Journal of Advances in Internal Medicine. 2:52-60
ISSN:	2091-1440 2091-1432
DOI:	10.3126/jaim.v2i2.8777
Popis:	Background and aims: The Helicobacter pylori (H. pylori) prevalence in Asian countries is highly variable, with higher seroprevalence shown in the previous studies of developing Asian countries. We aimed to determine the current H. pylori prevalence, correlate with gastroduodenal diseases and study gastric cancer incidence in Nepal. Methods: Among 3357 patients referred for endoscopy, 2820 eligible patients underwent upper gastrointestinal endoscopy with biopsy; H. pylori was considered positive when either of Rapid Urease Test (RUT) or histopathology showed positive result. Results: The H. pylori prevalence was 29.4% in overall distribution, 41.1% in gastritis and or duodenitis, 69.5% in gastric ulcer, 84.7% in duodenal ulcer, 20.8% in gastric polyp and 11.5% in gastric cancer. The H. pylori infection was significantly associated with gastritis and or duodenitis [P
Databáze:	OpenAIRE
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