Gliadin-induzierte Migrationshemmung peripherer Leukozyten in der Agaroseplattentechnik bei Patienten mit Coeliakie
| Autor: | Hanke R, Lippmann-Nielsen I, Douwes Fr |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
biology
business.industry nutritional and metabolic diseases Cell Migration Inhibition General Medicine medicine.disease Ulcerative colitis digestive system diseases Coeliac disease Peripheral chemistry.chemical_compound Diarrhea chemistry Immunology medicine biology.protein Agarose Pancreatitis medicine.symptom business Gliadin |
| Zdroj: | DMW - Deutsche Medizinische Wochenschrift. 102:721-724 |
| ISSN: | 1439-4413 0012-0472 |
| DOI: | 10.1055/s-0028-1104960 |
| Popis: | Sensitisation to gliadin was studied--using a modified leucocyte-migration inhibtion test after Clausen--in patients with coeliac disease (10 patients), ulcerative colitis (9), terminal ileitis (9), bacterial diarrhoea (9), and other gastro-intestinal diseases (14). Only the group of patients with coeliac disease had such specific sensitisation. The migration index, at 0.72 +/- 0.06, was significantly lower in them than in other groups. This reaction is disease-specific and indicates that in coeliac disease cellular immune mechanisms also play a role. The specificity of the reaction can also be used diagnostically. |
| Databáze: | OpenAIRE |
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