Choleragen-induced changes in the ultrastructure of epitheliocytes from the large intestine of conventional and gnotobiotic minipigs

Autor:	V. A. Shakhlamov, I. V. Isupov, L. A. Nazarova
Rok vydání:	1996
Předmět:	Toxin Cholera toxin General Medicine Biology medicine.disease_cause Mucus General Biochemistry Genetics and Molecular Biology Microbiology Cell biology Paracrine signalling medicine.anatomical_structure Organelle medicine Ultrastructure Secretion Large intestine sense organs
Zdroj:	Bulletin of Experimental Biology and Medicine. 122:1248-1250
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf02445207
Popis:	The dynamics of changes in the absorbing epitheliocytes and goblet cells is studied in minipigs 1, 3, 6, 18, and 24 h after intragastral administration of cholera toxin. Light and dark cells are identified after the treatment. The dark cells are probably protected against the toxin by paracrine Ec-cells persisting throughout the entire observation period. Changes in the organelles of absorbing epitheliocytes appear 3 h after the treatment and persist for 24 h. During this period, the goblet cells actively secrete mucus.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::207812375b6dcbaa103403b90411e009 https://doi.org/10.1007/bf02445207 Zobrazit plný text záznamu Full text from SpringerLink