Echocardiographic evaluation of propranolol therapy for mitral valve prolapse

Autor: Roger A. Winkle, Daniel J. Goodman, Richard L. Popp
Rok vydání: 1976
Předmět:
Zdroj: Heart. 38:129-134
ISSN: 1355-6037
DOI: 10.1136/hrt.38.2.129
Popis: This study evaluates the effect of propranolol on the echocardiogram of 8 patients with late systolic mitral valve prolapse. Echocardiograms were performed with the patients on no medication and again while on oral propranolol therapy. Propranolol caused a statistically significant increase in left ventricular volume; however, neither the echocardiographic pattern nor the timing of mitral valve prolapse was altered by propranolol. These findings suggest that factors in addition to left ventricular volume play a role in regulating valvular dysfunction in this condition.
Databáze: OpenAIRE