Yeast prions as epigenetic determinants

Autor: Mick F. Tuite, Wesley R. Naeimi
Rok vydání: 2010
Předmět:
Zdroj: The Biochemist. 32:30-33
ISSN: 1740-1194
0954-982X
DOI: 10.1042/bio03205030
Popis: In the mid-1960s, two unusual genetic determinants were discovered in the yeast Saccharomyces cerevisiae. In genetic crosses, these determinants, called [PSI+] and [URE3] respectively, were found not to be inherited according to Mendel's laws. Little did the researchers realize at the time that the non-Mendelian elements they had stumbled upon were in fact two different yeast prions – although definitive evidence of this only emerged some 30 years later1.
Databáze: OpenAIRE