Yeast prions as epigenetic determinants
Autor: | Mick F. Tuite, Wesley R. Naeimi |
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Rok vydání: | 2010 |
Předmět: | |
Zdroj: | The Biochemist. 32:30-33 |
ISSN: | 1740-1194 0954-982X |
DOI: | 10.1042/bio03205030 |
Popis: | In the mid-1960s, two unusual genetic determinants were discovered in the yeast Saccharomyces cerevisiae. In genetic crosses, these determinants, called [PSI+] and [URE3] respectively, were found not to be inherited according to Mendel's laws. Little did the researchers realize at the time that the non-Mendelian elements they had stumbled upon were in fact two different yeast prions – although definitive evidence of this only emerged some 30 years later1. |
Databáze: | OpenAIRE |
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