New route to the synthesis of the illudane skeleton by Michael–Michael-elimination reaction

Autor:	Hiroto Nagaoka, Yasuhiro Kanemitu, Kazuo Tokuzaki, Takehiko Yoshimitsu
Rok vydání:	2000
Předmět:	Elimination reaction Chemistry Stereochemistry Organic Chemistry Drug Discovery Optically active Skeleton (category theory) Ring (chemistry) Biochemistry
Zdroj:	Tetrahedron Letters. 41:5923-5926
ISSN:	0040-4039
Popis:	A new route to the synthesis of an optically active illudane skeleton from ( R )-(−)-pantolactone ( 4 ) is established. The tricyclic ring system was constructed by Michael–Michael-elimination reaction of the enolate of (3 S ,5 R )-3-( tert -butyldimethylsilyloxy)-5-methoxymethyloxy-1-propionylcyclopentene ( 10 ) with ethyl cyclopropylidenacetate ( 3 ).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2056d9eaad7f4cd86f98af0324f80174 https://doi.org/10.1016/s0040-4039(00)00974-6 Zobrazit plný text záznamu Full Text from ScienceDirect