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Objectives To demonstrate the presence of mineral metabolism disorders and lithogenic factors in the urine of patients with osteoporotic fracture without previously known stones. Material and methods 67 patients with osteoporotic fractures surgically treated in trauma service are included. The area of the fracture site, fracture mechanism and the presence of osteoporosis were the factors taken into account to diagnose osteoporotic fracture. Mineral metabolism, calciuria, oxaluria, uricosuria and citraturia in 24-h urine were analyzed. The presence of abnormal calcium and phosphorus metabolism was proved comparing hypercalciuria patients with normocalciuria ones. Results 12 men and 55 women with mean age 68.8 ± 14.5 years old were included. Mean body mass index (BMI) was 27.4 ± 4.1 kg/m 2 . 42% of patients showed hypercalciuria, 34% hyperoxaluria, 34% hypocitraturia and 7% hyperuricosuria. Statistically significant differences were observed only in fasting calcium/creatinine ratio (0.17 versus 0.08; p Conclusions Patients with osteoporotic fractures show different lithogenic factors in urine, mainly hypercalciuria, always in fasting conditions. |
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