Clinical Patterns of Hair Loss in Men
| Autor: | Natalie Kash, Adam Leavitt, Spencer Hawkins, Rahil B. Roopani, Matt Leavitt |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
integumentary system
business.industry Wnt signaling pathway Prostaglandin Inflammation Dermatology Bioinformatics medicine.disease_cause medicine.disease Pathophysiology 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Vasculogenesis Hair loss chemistry 030220 oncology & carcinogenesis Dihydrotestosterone medicine medicine.symptom business Oxidative stress medicine.drug |
| Zdroj: | Dermatologic Clinics. 39:361-370 |
| ISSN: | 0733-8635 |
| DOI: | 10.1016/j.det.2021.03.001 |
| Popis: | A number of pathways and factors including oxidative stress, inflammation, prostaglandins, vasculogenesis, Wnt/β-catenin, and transforming growth factor-β have been shown to be important in male androgenetic alopecia. There is limited but increasing evidence of the potential usefulness of antioxidants, anti-inflammatory agents, prostaglandins, and growth factors for treating of androgenetic alopecia. Lifestyle factors and comorbidities including cardiovascular risk factors have been shown to be associated with male androgenetic alopecia. Further study of these pathways, factors, and comorbidities is needed to better understand the pathophysiology, find potentially useful therapeutic targets, and ensure a comprehensive approach to the management of androgenetic alopecia in men. |
| Databáze: | OpenAIRE |
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