Familial Clustering of Antiphospholipid Syndrome

Autor:	Sana Haseeb Khan, Asma Saadia, Muhammad Dilawar Khan
Rok vydání:	2019
Předmět:	Pediatrics medicine.medical_specialty Future studies business.industry Familial clustering General Medicine Disease medicine.disease Asymptomatic Thrombosis Systemic autoimmune disease Antiphospholipid syndrome Medicine medicine.symptom business
Zdroj:	Journal of the College of Physicians and Surgeons Pakistan. 29:1221-1224
ISSN:	1681-7168 1022-386X
DOI:	10.29271/jcpsp.2019.12.1221
Popis:	Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterised by thrombosis (venous or arterial) and/or pregnancy-related complications. There is very scanty literature available regarding familial occurrence of APS worldwide and to the best of our knowledge, this important aspect has never been previously reported from Pakistan. We are presenting three patients of a Pakistani family who presented with thrombotic and pregnancy-related complications. Screening of the asymptomatic family members was also carried out. Knowledge about the familial occurrence of the disease is important not only for better management of such patients but also to emphasise the need for future studies to unveil its genetic basis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::203cf59c7afa97217975f0421e5f73e2 https://doi.org/10.29271/jcpsp.2019.12.1221 Zobrazit plný text záznamu