P70-T Results of neurophysiological tests in a child with pandysautonomia

Autor: Marek Kaciński, Aleksandra Gergont, Sławomir Kroczka
Rok vydání: 2019
Předmět:
Zdroj: Clinical Neurophysiology. 130:e59
ISSN: 1388-2457
DOI: 10.1016/j.clinph.2019.04.431
Popis: Background Pandysautonomia can be associated not only with acute loss of autonomic functions leading to syncopes, blood pressure and heart rate changes but also can affect afferent functions of peripheral nerves, resulting in loss of motor functions. Aim The aim of this study was to present tests to the evaluate autonomic function that are available to the clinician and significance of neurophysiological methods in the differential diagnosis of dysautonomia. Methods We present a case report of a 16-year-old girl, admitted to the hospital after syncope. Two months earlier she suffered from upper respiratory tract infection, followed by severe gastroparesis, urine retention, sweating and pupillary disturbances. On the first day of hospitalization the child refused to walk. Several tests including electromyography, electroneurography, miastenic test, videoelectroencephalography and head-up tilt test with electrocardiography were performed. Biofeedback as one of therapeutic methods was introduced. Results Autoimmune autonomic ganglionopathy was diagnosed with the postural orthostatic tachycardia syndrome. A significant clinical improvement was achieved after plasma exchange. Conclusion Generalized autonomic failure can occur as a result of many diseases that affect autonomic pathways. The role of electrophysiological methods and autonomic testing is to increase sensitivity and specificity in the detection and differentiation of dysautonomia.
Databáze: OpenAIRE
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