Antibody to Hepatitis G Mrus after a Vapour-Heated Factor Vlll Goncentrate

Autor:	R. De Biasi, P. M. Mannucci, A. Chistolini, A.R. Zanetti, G. Tamponi, R. Musso, Massimo Colombo
Rok vydání:	1990
Předmět:	Clotting factor HBsAg biology business.industry Hepatitis C virus Hematology Hepatitis C Hepatitis B medicine.disease_cause medicine.disease Virology Coagulopathy biology.protein Medicine Viral disease Antibody business
Zdroj:	Thrombosis and Haemostasis. 64:232-234
ISSN:	2567-689X 0340-6245
DOI:	10.1055/s-0038-1647291
Popis:	SummaryTo evaluate whether or not clotting factor concentrates exposed to virucidal procedures transmitted hepatitis C, sera obtained in 1984–1986 from 27 previously untreated hemophiliacs infused with a vapour-heated factor VIII concentrate were tested retrospectively for the antibody to the hepatitis C virus (anti- HCV). A 2-year-old hemophiliac, negative for anti-HCV before administration of concentrate, seroconverted at week 12 and remained anti-HCV positive thereafter. Both his parents were anti-HCV negative and he had no other household contact. The patient had also become HBsAg positive at week 8 and had at the same time a marked elevation of alanine aminotransferase. His double infection with the hepatitis B and C viruses indicates that hot vapour was not completely effective in inactivating these viruses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1ff01e6f7a78d0a7c24144a1dacae9a3 https://doi.org/10.1055/s-0038-1647291 Zobrazit plný text záznamu