Erythrocyte-damaging and immunomodulating action of retinoids

Autor: O. I. Mikhailov, Yu. T. Volkov, Yu. I. Afanas'ev, V. I. Nozdrin, S. M. Subbotin, S. A. Nikiforov, G. A. Kosolapov
Rok vydání: 1985
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 100:1398-1401
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00837871
Popis: The influence of retinyl acetate, retinoic acid and its esterified cis- and trans-derivatives, retinoids C15 and C20 on erythrocytes, liver macrophages and white pulp of the spleen was studied in the experiments on mice of different strains. It was found that administration of these compounds leads to the damage of the blood cells, increase in the number of liver macrophages and the share of white pulp in the spleen and stimulation of the local response to tuberculin. The interdependence of changes in the blood and adjuvant is suggested.
Databáze: OpenAIRE