A Case of Orbital Granulocytic Sarcoma (Chloroma) Well Responded to the Treatment
| Autor: | Lokman Balyen, Pasa Semir, Deniz Balyen Ls |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Oncology medicine.medical_specialty Chemotherapy Leukemic Infiltration Medullary cavity business.industry medicine.medical_treatment medicine.disease Surgery 03 medical and health sciences Leukemia 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure hemic and lymphatic diseases 030220 oncology & carcinogenesis Internal medicine Materials Chemistry medicine Myeloid sarcoma Sarcoma Sarcoidosis Bone marrow business |
| Zdroj: | Advances in Ophthalmology & Visual System. 5 |
| ISSN: | 2377-4290 |
| Popis: | Granulocytic sarcoma (GS), myeloid sarcoma (MS) or extra medullary leukemic deposits is an unusual manifestation of AML, accounting for about 3% of acute leukaemia’s. GS may occur as a manifestation of a systemic myelogenic leukaemia or it may precede systemic manifestations of peripheral blood and bone marrow. When GS precedes the development of systemic leukemia the diagnosis can be difficult for clinicians. Owing to the rarity of GS there are no large studies analyzing prognostic factors in these patients. The presence of MS at diagnosis in a leukaemic patient was traditionally considered to represent a marker for poor clinical outcome and shorter survival. Herein, we described a patient with newly diagnosed AML and right orbital GS which treated with standard chemotherapy regime and responded dramatically in two weeks. An extra-medullary leukemic infiltration is a bad prognostic sign, because it might act as a reservoir for proliferation of leukaemic cells and an eventual relapse. In addition to good medical response of our case we want to note that a variety of ophthalmologic findings can be seen in leukaemia’s. Careful and detailed ophthalmologic examination plays crucial role in timely diagnosis of many curable disordered including leukaemia’s and has vital importance on the management of leukaemia’s. |
| Databáze: | OpenAIRE |
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