| Autor: |
E.A. Cerny, Carl Peraino, Y.E. Rahman |
| Rok vydání: |
1969 |
| Předmět: |
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| Zdroj: |
Biochimica et Biophysica Acta (BBA) - Enzymology. 178:68-73 |
| ISSN: |
0005-2744 |
| DOI: |
10.1016/0005-2744(69)90132-6 |
| Popis: |
A relationship was found between the activity of three ribonucleases and liver growth. All three liver ribonucleases showed high activity in fetuses 3 days before birth, in new-borns and in suckling rats; these enzyme activities decreased gradually and attained the adult level between 30 to 40 days of age. Acid phosphatase was relatively constant during the developing stage of the rat. Acid ribonuclease (i.e., ribonuclease I) increased soon after feeding 2-acetyl-aminofluorene while acid phosphatase decreased. Ribonuclease II and ribonuclease III increased during the first 5–6 weeks and decreased subsequently for approx. 10 weeks before returning to the control level. In regenerating liver, all three ribonucleases were increased soon after partial hepatectomy with a maximal increase at about 4 h after the operation. Ribonuclease II activity was significantly decrease from 8 h to 24. Ribonuclease I and ribonuclease III remained increased up to 72 h after partial hepatectomy. The possible implications of the relationship between ribonuclease activities and phenomena of liver growth is discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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